Selective removal of anti-double-stranded DNA antibodies by immunoadsorption with dextran sulphate in a patient with systemic lupus erythematosus.
نویسندگان
چکیده
A dextran sulphate gel column removed anti-double-stranded DNA antibodies (anti-dsDNA) selectively, efficiently, and safely from the circulation of a patient with systemic lupus erythematosus (SLE). The mechanism of the removal is thought to be due to cross reactivity of anti-dsDNA with dextran sulphate, which has negatively charged units. Selective removal of anti-dsDNA is expected to contribute not only to the treatment but also to elucidation of the pathogenesis of SLE.
منابع مشابه
Selective removal of anti - double - stranded DNA antibodies by immunoadsorption with dextran sulphate in a patient with systemic lupus
A dextran sulphate gel column removed anti-double-stranded DNA antibodies (antidsDNA) selectively, efficiently, and safely from the circulation of a patient with systemic lupus erythematosus (SLE). The mechanism of the removal is thought to be due to cross reactivity of anti-dsDNA with dextran sulphate, which has negatively charged units. Selective removal of antidsDNA is expected to contribute...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 48 10 شماره
صفحات -
تاریخ انتشار 1989